The introductory sequence introduces the player to their character's father James, a doctor and scientist in свод, хранилище 101. James frequently makes Комментарии about the player character's deceased mother Catherine, and her Избранное Bible passage, Revelation 21:6, which speaks of "the waters of life".
The main quest begins after the player is forced to flee свод, хранилище 101 when James leaves the vault, throwing it into anarchy and causing the paranoid Overseer to send his police force after the player. The Поиск for James takes the character on a journey through the Wasteland, first to the nearby town of...
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