For one Ron would need a new girlfriend. I feel like there'd be a few more but I can't think of them off the top of my head. It seemed like their friendship blossomed enough for it to work out without much hassle.

I can sort of see the possibility in the movies, but in the books? Just no. I don't see it at all.

Harry would need to show some jealousy over Hermione's earlier love interests. He'd need to stop referring to her as "like a sister". I doubt Hermione would still have been giving him advice about Cho in that scenario. And like zanhar1 said, we'd need an alternate love interest for Ron definitely, and possibly one for Ginny too.

I agree with what Flickerflame said and want to add the following:

1. Harry would have to take notice of Hermione's eyes the first time he meets her on the Hogwarts Express and have a complimentary thought about them (i.e. her bright brown eyes) rather than waiting over a year later to notice them and just refer to them as brown.
2. Harry wouldn't think of Hermione sounding like an angry, hissing goose.
3. Hermione would laugh at more of Harry's jokes.
4. Hermione would have sleek, shiny hair or Harry would show a preference to girls who had bushy hair.
5. Harry would come to Hermione's defense right away when she was called a Mudblood as opposed to needing four days of built-up anger for him to do so.
6. He wouldn't think of her voice as being shrill and panicky.
7. Harry would have been the one to call out Snape for calling Hermione a know-it-all.
8. Harry (polyjuiced as Goyle) would have been the one to have the urge to punch Draco when Draco said he hoped she'd be the first Mudblood to be killed.

Way too many changes for it to work properly. Swap the early Ron/Hermione hints for hints of Harry and Hermione, perhaps show them being a little antagonistic towards each other in Goblet of Fire...

Well, the zero changes option obviously has to be left out, as the change from Romione to Harmony as endgame has to be made. ;). So I don't understand why anyone would vote for zero changes. Also, why the sudden jump from 3-5 to 15+? The numbers between 5 and 15 don't exist?
But honestly, that shrill and panicky nonsense again? Hermione just saw a Dementor try to suck out Harry's soul. Why did her voice sound shrill and panicky? Gee, maybe because she was PANICKING?

And why alternate love interests for Ron and Ginny? Luna and Draco also married characters we knew nothing about, it's not like Ron and Ginny could have done the same. Also, why have Harry defend Hermione ALL THE TIME? It would make him look obsessed and would make Ron literally just the third wheel if he'd never support his other friend.

Antagonistic in GoF? Why? Have you already forgotten about the fight they had one book earlier over the Firebolt? Or HBP, the arguments over the book?
Nope, I don't think we need that many changes. Ron won't come back in DH, and thus Snape has to send his patronus to the tent to warn Hermione, so she can save him from drowning instead of Ron. We'll get an interesting part with the locket in which Hermione sees RiddleHarry snogging RiddleGinny which ends Hermione reminding RiddleGinny that while Ginny may be more beautiful, she'll never know the real Harry the way Hermione knows him. And of course, after Harry's realisation at the Yule Ball how amazingly beautiful Hermione is, the whole Cho-subplot becomes redundant.

It will probably also include a change I'd like less: With Hermione firmly his soulmate, Luna's role would most likely be diminished as well. She's a great character, but why would Harry need her if he has his perfect soulmate Hermione whom he trusts unconditionally and to whom he can tell everything?

I'll just reply to the first part, since the rest is just ramblings and delusion from a typical Harmony shipper (well the first part is too...).

There has been no change from Romione to Harmony. None whatsoever. JKR just said in some ways Harry/Hermione were a better fit. In some ways does not mean in all ways and it certainly does not mean that it is canon. She also said that Harry's love for Ginny is true. Obviously, there need to be many changes for Harmony to have happened.

But then again, facts enrage deluded Harry/Hermione shippers.

EDIT: obviously I misread your comment. But you still think it should have happened. Why you think that, is beyond me, because it's clear in the books that Harry belongs with Ginny and not Hermione.

Yeah, very funny, Stefan. You're so good at accusing people who don't follow your ship of rambling, and now you had to admit you even misread my comment which was just answering a question. Really man, get a life. (But why am I not surprised that when I again return after a few months you rear your ugly head again over here as well?)

Ha, ha, ha. You judge without knowing. If you had gone on my profile page, you would notice that I have been active on this site before you "reared your ugly head"? But then again, I suspect you have a life, like I do.

And I'm not accusing all people of different ships of rambling. I have talked with several H/Hr shippers, and we respect each other. The difference between them and you (and other Harmonians) is that you are delusional.

@Stargaryen - Ron is much more of a main character than Neville or Luna. He's actually tied secondary main character with Hermione. That's why his love interest would have to be a character in herself, and you'd need to see that relationship built up through the story. The same would have happened to Hermione if Ron and Harry had both been gay and they'd been the final pairing from the three.

The difference between the arguments Harry and Hermione had and the ones Ron and Hermione had is that some of Ron and Hermione's were sparked by romantic jealousy. The one about Krum in their fourth year is the most obvious. If Harry and Hermione were to be endgame, you'd need some sign of jealousy. There would also not have been the obvious build-ups of Harry/Ginny and Ron/Hermione in book 6.

Stargaryen- You said "But honestly, that shrill and panicky nonsense again? Hermione just saw a Dementor try to suck out Harry's soul. Why did her voice sound shrill and panicky? Gee, maybe because she was PANICKING?"

Bzzzt! Wrong.

What would they say if Harry wrote to them [Ron and Hermione] and told them his scar was hurting?
At once, Hermione Granger's voice seemed to fill his head, shrill and panicky. (GoF, pg 21)

@Flickerflame, as so many people repeatedly have pointed out, Harry Potter is not a love story. So why would Ron alternative love interest be a character in itself? If it's not relevant to the plot, leave it out. Harry on the other hand needs to know love because it's "The-Power-The-Dark-Lord-Knows-Not&qu­ot;­.

Also, why does jealousy equal romance? Ever heard of this song by Sting, "If you love somebody set them free"? Well, if that kind of romance is something you like, feel free to enjoy it. I'm personally more interested in romance based on trust and respect. But I guess that's a "cliché".

@Pensieve_Seeker. OK, so you refer to Harry thinking about how Hermione would react if he told his scar was hurting. Fine. But where has it ever been written Harry hates that type of voice? And why does Harry think her voice will be shrill and panicky? Gee, I don't know, maybe it's a memory of how Hermione reacted before when something bad happened to Harry.

@stefanvh_hpgw: Ah, the 'delusional' argument again. Nothing new under the sun. Did Emerson Spartz already message you to ask if you could become his parrot? And no, I did not check your profile. Unlike you, I'm not interested in stalking.

If only Harry's love is relevant to the plot, why did Ron and Hermione become a pairing? Why did other pairings, such as Fleur and Bill, and Remus and Tonks, exist? I stick to my point that Ron is too important of a character to throw in a love interest only in interviews after the books were published.

Ok, it wouldn't be fully necessary to have jealousy. Jealousy is just one of the ways to introduce the idea of a pairing, showing one character jealous when the other is dating someone else. But there would still need to be some hint of the pairing: whether jealousy, or finding the other attractive on a regular basis, or disliking the other's love interest and finding excuses for that..... there's no hint at all for Harry and Hermione. Not compared to the canon pairings. Those hints would need to be turned around and put between Harry and Hermione for that pairing to have become canon.

Also, "shrill and panicky" is generally seen as a negative description. It's definitely not flattering. It's not the way someone would think of a love interest's voice. If Harry and Hermione were meant to be a couple, he'd either describe her voice differently there or there'd be a much more flattering description, with possibly regret for the earlier one, later on in the books.

@Stargaryen: No, I haven't received any message from Emerson. It wouldn't hurt, though.

And I would accept your explanation about "shrill and panicky' if it weren't for the fact that Harry often describes Hermione's voice as talking bossily, shrilly, loftily, huffily, as well as shrieking, snapping, etc. It is most certainly not a one off.

Flickerflame- You said "Also, "shrill and panicky" is generally seen as a negative description. It's definitely not flattering. It's not the way someone would think of a love interest's voice. If Harry and Hermione were meant to be a couple, he'd either describe her voice differently there or there'd be a much more flattering description, with possibly regret for the earlier one, later on in the books."

Exactly. JKR didn't write that Hermione's voice was calm and soothing when it filled Harry's head. She wrote that it was shrill and panicky. Now, who else in this story would Harry associate with having a shrill voice? Oh! I know!

Yet Harry Potter was still there, asleep at the moment, but not for long. His Aunt Petunia was awake and it was her shrill voice that made the first noise of the day. (SS/PS, pg 19)

Sure, shrill and panicky may not look like something positive, but (as stefan so often states), it's all about context. If Hermione goes into a panic by the mere thought of something bad happening to her best friend in canon, why would we want to make her sound like she cares much less in a hypothetical alternate universe where Harry is the love of her life. I'd even keep the shrieking, bossily, etc. in, because true love is all about accepting your love for who (s)he is, with all her good qualities as well as her flaws. Nobody is perfect. If you only want the good, but can't accept the bad, then that's not true love at all.

Hermione speaks in the ways I outlined above for much lesser reasons, not just because of Harry's life being in danger. And as said above, there would have to be a realization and regret that he viewed her in that way, something which obviously was not in the books.