Mine's a mixture, I know that pairings like Polivia, Delena, Tiva and MSR are fairly well known but ones like Gormes and Jack/Claire are not as well known.

chair
derena
quick
delena
jate
pb&j
naley
brulian
cherry
pesmond

most of them are fairly well knows :)

some very well known like Jate or Huddy or B&B.
Some kinda known but still with not enough fans like LoVe.
And some couples that almost nobody seems to know about like Felicity\Ben or Maddie\David <3

Tony and Ziva, Mulder and Scully, Chuck and Sarah, Penny and Sheldon, Rizzoli and Isles, Peter and Olivia, Piper and Leo, Niles and Daphne, Abby and McGee + Castle and Beckett. :)

Well known:
Buffy&Spike
Rachel&Puck
Luke&Lorelai
Logan&Veronica
Booth&Brennan
Brooke&Lucas

Hardly anyone knows Brian&Justin or Jack&Ianto (which I find pretty sad, that the two obscure couples in my top ten are both gay :P)...
And I see Ten&Rose and Angel&Cordelia as sort of in the middle.

I'd say most of my ships are from well known shows.
Fringe/Polivia need more love though.

Mulder & Scully
House & Cuddy
Peter & Olivia
Castle & Beckett
Brooke & Julian
Tony & Ziva
Sam & Addison
Lois & Clark
Monica & Chandler
Penny & Sheldon

I don't ship any obscure pairings probs some fairly unknown ones, but thats due to the popularity of the show!

well known:

-Damon/Elena (TVD) (OTP!!!)
-Eric/Sookie (TB)
-Annie/Liam (90210)
-Meredith/Derek (Grey's Anatomy)
-Matt/Caroline (TVD)
-Puck/Quinn (Glee)
-Cook/Effy (Skins)
-Aria/Ezra(not so well known) (PLL)

not so well known:

-Richard/Kahlan (Legend Of The Seeker) one of my favorite couples EVER! amazing show!!!
-Arthur/Morgana (Merlin)

House and Cuddy- Well Known
Mac and Stella- Not so well known
Hotch and Emily- Not so well known
Tony and Ziva- Well Known
Booth and Brennan- Well Known
Grissom and Willows- Not so well known
Rizzoli and Isles- Not so well known
Chase and Thirteen- Not so well known
Mulder and Scully- Well Known
Piper and Leo- Well Known

It's half and half.

The majority of my top 10 are well known except for 2

Brooke/Lucas - Well Known
Spike/Buffy - Well Known
Sawyer/Juliet - Well Knownish
Nathan/Haley - Well Known
Xander/Anya - Not so well known
Aden/Belle - Not so well known
Chuck/Blair - Well Known
Seth/Summer - Well Known
Dan/Serena - Well Known
Piper/Leo - Well Known

Well known:
-Spike/Buffy
-Damon/Elena
-Logan/Veronica
-Booth/Bones
-Cole/Phoebe

Not so well known:
-Lee/Kara
-Angel/Darla
-Wesley/Lilah
-Ryan/Taylor
-Rory/Logan

Haha, half and half ;)

My top 10 changes lots, but it's pretty much

Well known:
Rory/Jess
Luke/Lorelai
Pacey/Joey
Logan/Veronica
Spike/Buffy
Barney/Robin
Jim/Pam
Jake/Peyton

Less known:
Shannon/Sayid
Lucy/Carter

1. Peter and Darcy
2. Jay and Emma
3. KC and Jenna
they're all from Degrassi

My top ten is always changing! But its a pretty even mix of lesser known ships and well known ships. Right now my top ten are:

Pacey/Joey (Well Known)
Luke/Lorelai (Well Known)
Cate/Baze (Lesser Known)
Spike/Buffy (Well Known)
Liam/Annie (Well Known)
Brooke/Haley (Might be alone on that ship! ;) LOL)
Cara/Leo (Lesser Known, almost obscure)
Sawyer/Juliet (Middle Ground)
Damon/Elena (Well Known)
Puck/Quinn (Well Known)
About half-an-half as I thought! ;)

There is only one couple I love that won't be well known here or by anyone that doesn't watch Hollyoaks or hasn't heard the show or whatever lol and that being John-Paul and Craig. But generally, the couples I ship are well known:

Damon and Elena
Jack and Kate
Brooke and Lucas
Spike and Buffy
Serena and Nate
Cook and Effy
Puck and Rachel
Eric and Sookie
Chandler and Monica

Some of them are really well known and accepted, like Mulder & Scully or Damon and Elena, but some are more obscure like Dean and Haley (crossover couple) or John Paul and Craig...it just depends! lol

Gavin and Stacey are the only ones that aren't well known. The other nine are.

All from famous shows :)

10.Dean&Jo (Supernatural)
9.Brooke&Julian (OTH)
8.Damon&Elena (TVD)
7.Stefan&Elena (TVD)
6.Baze&Cate (Life Unexpected)
5.Dan&Serena (GG)
4.Navid&Adrianna (90210)
3.Luke&Lorelai (Gilmore Girls)
2.Chuck&Blair (GG)
1.Lucas&Peyton (OTH)

1.Tony & Ziva(NCIS)
2.Trip & T'Pol(ST:ENT)
3.Booth & Brennan(Bones)
4.Peter & Olivia(Fringe)
5.House & Cuddy(House)
6.Michael & Fiona(Burn Notice)
7.Castle & Beckett(Castle)
8.Anglea & Hodgins(Bones)
9.Annie & Auggie(Covert Affairs)
10.Shawn & Juliet(Psych)
I don't think any of those are too obscure...except for maybe Trip&T'Pol cuz they are from Star Trek: Enterprise...

Tony/Ziva (NCIS)
Jack/Sam (Stargate SG1)
Sharon/Andy (Major Crimes)
Emma/Killian (Once Upon a Time)
Barney/Robin (HIMYM)
Mal/Inara (Firefly)
Peter/Olivia (Fringe)
Adama/Roslin (BSG)
Jake/Amy (B99)
Robin/Regina (Once Upona Time)